frontimage

Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Insulin is a hormone that regulates blood sugar. Hyperglycaemia, or raised blood sugar, is a common effect of uncontrolled diabetes and over time leads to serious damage to many of the body’s systems, especially the nerves and blood vessels.

In 2014, 8.5% of adults aged 18 years and older had diabetes.
In 2015, diabetes was the direct cause of 1.6 million deaths.
Source the World Health Organisation.

Type 2 diabetes (formerly called non-insulin-dependent, or adult-onset) results from the body ineffective use of insulin. The majority of people with diabetes around the world, has type 2 diabetes, and is largely the result of excess body weight and physical inactivity.

There are several devises available to monitor blood sugar levels, one of them is the egm1000 non invasive glucose monitor .


egm1000

egm1000photo

non invasive glucose monitor

the egm1000 is produced by Evia Medical Technologies Ltd, United Kingdom. www.egm1000.com the egm1000 is distributed in Nigeria by Kainico. reception@diabetesnigeria.com

egm1000package

European Union authorisation n. 3901411CE01
Nigeria NAFDAC authorisation n. 03-6594

For Diabetics type 2 and pre-diabetics, above 16 years.Measures the tissue glucose.Is calibrated to the user once, when starting to use a new ear-clip. Price includes calibration at a nearby clinic/endocronologist. Now available in Nigeria.



The egm1000 measures your diabetes in three ways

Each technology measures different tissue parameters that are affected by the same change in glucose concentration, but is confined by the impact of interfering factors, due to lack of specificity. Therefore, a simultaneous evaluation of the above mentioned physiological changes through measurement of different sets of tissue perturbations, induced by changes in glucose concentration, increases the validity of the end result. The three independent readings are combined together by a proprietary algorithm, which calculates their weighted average.

Ultrasound

(phase shift as a function of speed of sound change within the tissue) – An ultrasonic wave travels from a transmitter, placed on one side of the earlobe, through the earlobe tissue and received at the other side. Zips et al [1] showed that the sound velocity depends linearly on the glucose concentration in a water-glucose solution. They also described sound velocity dependency on temperature. Moreover, the temperature dependence is more significant than that of the glucose concentration. One should note that these dependencies are not opposite to each other, meaning in the hyperglycemic range, the temperature increases as well as the concentration and thus the velocity of sound is expected to increase significantly. Furthermore, in live tissues, the influence of glucose concentration on the velocity of sound is more profound than the demonstration in Zips and associates’ study. This is since glucose-induced water transport affects tissue density as well as compressibility and they also affect the sound velocity [2].

Electromagnetic

workingwoman2

(conductivity of the tissue) – The device has two parallel foils, which act like capacitor’s plates. Thus the earlobe utilizes as a dielectric material between the two capacitor plates. Voltage application between the two plates stimulates the earlobe tissue, current measurement allows for impedance assessment. This method is plausible as a glucose assessment technique since plasma glucose induces ion shift across the cellular membrane in red blood cells and as a result changes membrane potential [3]. Furthermore, Hayashi et al [4] demonstrated that variations of the metabolically active enantiomer d-glucose affect the permittivity and conductivity of the cellular membranes. Tissue impedance is changed due to changes in blood glucose concentration and is therefore monitored [5].

Thermal

(heat capacity of the tissue) – A known (controlled) amount of energy is applied to the earlobe using a heat source for a predetermined period of time. The temperature developed on the earlobe as a result of the heating is glucose dependent, according to the bio-heat transfer equation, which describes the thermal properties changes of a living tissue [6].


Pricing

The egm1000 is a certified medical device. A decade was spent on developing the technology and perfecting it to reach the accuracy required for approval by the different countries Ministries of Health.

Sticking your finger to draw your blood is free, but the strips that you use cost in Nigeria around USD 60cents each. Your Endocronologist has probably asked you to measure after each meal, so 3 times per day. In 10 years this comes to USD 6 570 in strips plus the cost of the device around USD 40.

The egm1000 is available for around USD 2300 calibration included. The earpiece is replaced every 6 months. So for the same 10 years, the egm1000 will require 19 ear pieces * USD 150 per ear piece = 2850. Grand total is USD 5 150.

The economics becomes better the longer you use it. And because diabetes is a lifelong disease, regretfully, you are likely required to measure your glucose for many more years.

The real benefit however is difficult to measure in price. Because of the discomfort of drawing blood, many diabetics that are relying on strips, are over time likely to measure their glucose less and less. The reduced measuring increases the chance of us diabetics straying away from the lifestyle we need to live. The consequences may not be easy to see in the beginning, but once the symptoms start, can be dramatic.

easytousephoto

The story behind

The desire to develop a non-invasive glucose monitor came from one of the Evia founders, the late Dr. David Freger. David had diabetes and like many who suffer from this life-long debilitating disease, David was sick and tired of pricking his fingers to draw blood several times each day. Together with two of his trusted colleagues, they set out to develop a non-invasive glucose monitor that could provide pain-free measurements.

DeviceCloseUp

Following years of intense research and development they determined that the technical challenges of increasing the signal to noise ratio, to obtain a reliable reading without drawing blood, could best be achieved by combining three independent technologies simultaneously. They developed a proprietary and patented approach of using ultrasound, electromagnetic and thermal measurements with a unique algorithm to weigh each measurement and calculate the weighted average of the three readings. The development took a decade.

The device measures tissue/skin glucose and not blood glucose. So it is an indirect measurement. The glucose in the blood can be detected from the tissue/skin after some minutes.

There is a lot of noise inside the body that contributes to inaccuracy. It’s therefore hard to distinguish the glucose signal noninvasively from other parameters inside the body and from external factors such as temperature. So Evia decided to work with three technologies that reduce the noise rather than increase the signal as other technologies attempts to do.

The device was tested on more than 800 people prior to commercialization. It is intended for indoor use because readings are affected by wind and temperatures, needs to be within a range of 15 to 35 degrees Celsius. The device informs the user if he/she is outside temperature limits.

This innovative approach was recognized by Frost & Sullivan, who awarded the company a Product Innovation Leadership award. Frost & Sullivan is based in USA with 40 offices worldwide. They issue industry awards based on research.

David Freger passed away from diabetes complications at the age 48 in 2004. His colleagues completed the research and then the device. The egm1000 is a legacy that Dr David Freger left behind, to help persons with type2 diabetics. Today the egm1000 is sold in many countries and now also finally in Nigeria.


Frequently Asked Questions





EviaCool

insulin temperature shield

Did you know that Insulin deteriorates when exposed to warm weather ?

If you depend on insulin, keep your insulin with you. With this high-end device manufactured in England, have confidence that your insulin remains potent, whether you are at home close to your fridge, or whether you are far away, either on a plane or stuck in traffic.

EviaCool is a reusable temperature shield for insulin pens

EviaCool is intended to keep insulin cool within safe temperatures below 29°C (84.2°F) for a minimum of 12 hours even in a constant environmental temperature of 37.8°C (100°F), when the device is placed inside a personal handbag. The cap temperature regulation is passive and combines thermal insulation with heat absorbent material. The cap is reactivated/filled up to provide safe storage conditions, whenever the ambient temperature gets below 26°C (78.8°F), for subsequent periods of 12 hours and for up to 365 days (one year).

The insulin must always be at the manufacturer’s recommended temperature

Please refer to the insulin package insert of your specific insulin pen. The EviaCool fits most insulin pens sold in Nigeria.

To fully appreciate the importance of keeping your insulin within the recommended temperature, please ask your Endocronologist.

measure glucose
without drawing your blood

the egm1000,

now in Nigeria !


selected feedback

'I am so happy that I do not have to stick my finger anymore'

on egm1000 from Chief Kayode
'now I can test myself in front of other people, previously it could get a bit messy when I pricked my finger'

on egm1000 from Mr Abayomi
'it is accurate and I am happy'

on egm1000
from Mr Alex